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Search Results for " chronic lymphocytic leukaemia "

3

Compounds

Cat No. Product Name Synonyms Targets
T9925 Ofatumumab Others
Ofatumumab is a fully human monoclonal antibody to CD20 which appears to inhibit early-stage B lymphocyte activation
T4564 Ethacrynic acid Edecrin,Etacrynic Acid,Hydromedin Others , Calcium Channel , NF-κB , GST
Ethacrynic acid (Edecrin) is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the loop of Henle. It also inhibits glutathione S-transferase a...
T37602 GSK 143
Spleen tyrosine kinase (Syk) inhibitor (pIC50 = 7.5). Also inhibits phosphorylated Erk (pIC50 = 7.1). Decreases cell number and viability in chronic lymphocytic leukemia (CCL) cell lines. Liddle et al (2011) Discovery of...
TargetMol